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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP9A All Species: 23.03
Human Site: S433 Identified Species: 42.22
UniProt: O75110 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75110 NP_006036.1 1047 118583 S433 F S I Y T Q Q S Q D P P A Q K
Chimpanzee Pan troglodytes XP_514727 875 98509 A287 M S S R V H E A V K A I A L C
Rhesus Macaque Macaca mulatta XP_001098852 1044 118009 S430 F S I Y T Q Q S Q D P P A Q K
Dog Lupus familis XP_534457 1043 118292 S429 F S I Y T Q Q S Q D P P A Q K
Cat Felis silvestris
Mouse Mus musculus O70228 1047 118590 S433 F S I Y T Q Q S Q D P P A Q K
Rat Rattus norvegicus XP_002726328 995 111897 V407 G L D S M D E V Q S H I F S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509092 1116 127035 S502 F S I Y T Q Q S Q D P P A I K
Chicken Gallus gallus XP_417508 1115 125396 S501 F S I Y T Q Q S Q E P P A V K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038619 1108 125101 S480 I Q S Y A Q V S S A Q S N G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396589 1276 146194 E641 Q T C Y A N S E T S P V K P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799223 1105 125600 N491 L S A Y S Q S N H A G T A K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P98205 1107 124818 L417 A L K D A Q L L N A I T S G S
Baker's Yeast Sacchar. cerevisiae P40527 1151 130199 N545 Q S L V S S K N D S L N N S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 97.8 97.4 N.A. 97.9 89.7 N.A. 90.2 89.5 N.A. 71.3 N.A. N.A. 54.3 N.A. 60.4
Protein Similarity: 100 83.5 98.2 98.2 N.A. 99.5 91.8 N.A. 92.2 91.5 N.A. 82.4 N.A. N.A. 66.8 N.A. 74.4
P-Site Identity: 100 13.3 100 100 N.A. 100 6.6 N.A. 93.3 86.6 N.A. 20 N.A. N.A. 13.3 N.A. 26.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 13.3 N.A. 93.3 93.3 N.A. 20 N.A. N.A. 20 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 29 44.6 N.A.
Protein Similarity: N.A. N.A. N.A. 48.4 62.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 24 0 0 8 0 24 8 0 62 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 8 8 0 8 0 0 8 39 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 16 8 0 8 0 0 0 0 0 % E
% Phe: 47 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 0 0 8 0 0 16 0 % G
% His: 0 0 0 0 0 8 0 0 8 0 8 0 0 0 0 % H
% Ile: 8 0 47 0 0 0 0 0 0 0 8 16 0 8 8 % I
% Lys: 0 0 8 0 0 0 8 0 0 8 0 0 8 8 54 % K
% Leu: 8 16 8 0 0 0 8 8 0 0 8 0 0 8 0 % L
% Met: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 16 8 0 0 8 16 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 54 47 0 8 0 % P
% Gln: 16 8 0 0 0 70 47 0 54 0 8 0 0 31 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 70 16 8 16 8 16 54 8 24 0 8 8 16 24 % S
% Thr: 0 8 0 0 47 0 0 0 8 0 0 16 0 0 8 % T
% Val: 0 0 0 8 8 0 8 8 8 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 70 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _